Tanzanian President John Pombe Magufuli has died aged 61 Amidst Covid Rumours.
The President died on Wednesday in a hospital in Dar es Salaam, the country's Vice President has announced.
Magufuli had not been seen in public for more than two weeks, and rumours have been circulating about his health.
Opposition politicians said last week that he had contracted Covid-19, but this has not been confirmed.
Magufuli was one of Africa's most prominent coronavirus sceptics, and called for prayers and herbal-infused steam therapy to counter the virus.
"It is with deep regret that I inform you that today... we lost our brave leader, the president of the Republic of Tanzania, John Pombe Magufuli," Vice-President Hassan said in the announcement.
She said there would be 14 days of national mourning and flags would fly at half mast.
According to Tanzania's constitution, Ms Hassan will be sworn in as the new president and should serve the remainder of Magufuli's five-year team which he began last year.
Magufuli was last seen in public on 27 February, but Prime Minister Kassim Majaliwa insisted last week that the president was "healthy and working hard".
Magufuli declared Tanzania "Covid-19 free" last June. He mocked the efficacy of masks, expressed doubts about testing, and teased neighbouring countries which imposed health measures to curb the virus.
Tanzania has not published details of its coronavirus cases since May, and the government has refused to purchase vaccines.
John Pombe Joseph Magufuli was a Tanzanian politician who served as the fifth President of Tanzania from 2015 until his death in 2021. He served as Minister of Works, Transport and Communications from 2000 to 2005 and 2010 to 2015 and was chairman of the Southern African Development Community from 2019 to 2020.